产品货号 :  mlR16721

英文名称 :  TRIM

中文名称 :  T淋巴细胞受体相互作用分子抗体

别    名 :  HSPC062; pp29/30; T cell receptor interacting molecule; T-cell receptor-associated transmembrane adapter 1; T-cell receptor-interacting molecule; TCRIM; TRAT1; TRAT1_HUMAN; TRIM.  

研究领域 :  细胞生物  免疫学  信号转导  淋巴细胞  t-淋巴细胞  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Dog,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  21kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human TRIM:21-120/186

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍Function:

Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.

Subcellular Location:

Cell membrane.

Tissue Specificity:

Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level).

Post-translational modifications:

Phosphorylated on tyrosines by LCK or FYN upon TCR activation.

SWISS:

Q6PIZ9

Gene ID:

50852

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.