产品货号 :  mlR20027

英文名称 :  CTAGE1

中文名称 :  皮肤T细胞淋巴瘤相关抗原1抗体

别    名 :  Cancer/testis antigen 21.2; Cancer/testis antigen family 21 member 1; Cancer/testis antigen family 21 member 2; CT21.2; CTAGE 1; CTAGE 2; CTAGE; CTAGE1; CTGE2_HUMAN; Cutaneous T cell lymphoma associated antigen 1; Cutaneous T cell lymphoma associated antigen 2; Protein cTAGE-2.  

研究领域 :  肿瘤  细胞生物  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  85kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human CTAGE1:151-250/745

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   Cutaneous T-cell lymphoma-associated antigen 1 (CTAGE1) is normally expressed only in testis tissue, and is found in 35% of CTCL tissues, but not in any leukemia or melanoma cell lines. The gene encoding for CTAGE1 maps to chromosome 18p11.2. CTAGE2 is a longer variant of CTAGE1 and is translated from a different open reading frame. Three other splice variants related to the major CTAGE1 and CTAGE2 variants exist, some of which are expressed only in testis, while others are expressed in a wide range of adult and fetal tissues. CTAGE1 may be an important factor in the specific immunotherapy of cutaneous T-cell lymphoma and other malignancies.

Subcellular Location:

Membrane.

Tissue Specificity:

Testis. Not found in tumor.

Similarity:

Belongs to the cTAGE family.

SWISS:

Q96RT6

Gene ID:

64693

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.