产品货号 :  mlR17754

英文名称 :  MRFAP1

中文名称 :  T淋巴细胞活化蛋白MRFAP1抗体

别    名 :  Mof4 family associated protein 1; MORF4 family associated protein 1; OTTHUMP00000155159; OTTHUMP00000217763; PAM14; PGR1; Protein associated with MRG 14 kDa; Protein associated with MRG of 14 kDa; Protein PGR1; T cell activation protein.  

研究领域 :  肿瘤  细胞生物  免疫学  t-淋巴细胞  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Pig, Cow,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  15kDa

细胞定位 :  细胞核 细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human MRFAP1:51-127/127

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  This gene encodes an intracellular protein that interacts with members of the MORF4/MRG (mortality factor on chromosome 4/MORF4 related gene) family and the tumor suppressor Rb (retinoblastoma protein.) The protein may play a role in senescence, cell growth and immortalization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Function:

MRFAP1 is found in a complex composed of MORF4L1, MRFAP1 and RB1. It interacts via its N-terminus with MORF4L1. It also interacts with CSTB and MORF4L2.

Subcellular Location:

Nucleus. Cytoplasm; perinuclear region. Note: Colocalizes with MORF4L1 to cell nuclei.

Similarity:

Belongs to the MORF4 family-associated protein family.

SWISS:

Q9Y605

Gene ID:

93621

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.