产品货号 :  mlR2656

英文名称 :  LIR-6/LILRA1

中文名称 :  白细胞免疫球蛋白样受体6抗体

别    名 :  CD85 antigen-like family member I; CD85i; Leukocyte immunoglobulin-like receptor 6; Leukocyte immunoglobulin-like receptor subfamily A member 1; Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1; Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 soluble isoform; LILRA1; LIR-6; LIR6; LIRA1_HUMAN.  

研究领域 :  细胞生物  免疫学  细胞膜受体  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  52kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human LIR6:401-489/489

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍  :  This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

Function:

May act as receptor for class I MHC antigens.

Subcellular Location:

Membrane; Single-pass type I membrane protein.

Tissue Specificity:

Detected in monocytes and B-cells.

Similarity:

Contains 4 Ig-like C2-type (immunoglobulin-like) domains.

SWISS:

O75019

Gene ID:

11024

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.