产品货号 :  mlR16479

英文名称 :  ZNF774

中文名称 :  锌指蛋白774抗体

别    名 :  Zinc finger protein 774; ZN774_HUMAN; ZNF774.  

研究领域 :  转录调节因子  锌指蛋白  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  55kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human ZNF774:31-130/483

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   ZNF774 (zinc finger protein 774) is a 483 amino acid protein that localizes to the nucleus and contains 12 C2H2-type zinc fingers and a KRAB domain. One of several members of the Krüppel C2H2-type zinc-finger protein family, ZNF774 is thought to be involved in transcriptional regulation events. The gene encoding ZNF774 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Function:

May be involved in transcriptional regulation.

Subcellular Location:

Nucleus.

Similarity:

Belongs to the krueppel C2H2-type zinc-finger protein family.

Contains 12 C2H2-type zinc fingers.

Contains 1 KRAB domain.

SWISS:

Q6NX45

Gene ID:

342132

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片