产品货号 : mlR16449
英文名称 : ZNF799
中文名称 : 锌指蛋白799抗体
别 名 : HIT 40; HIT40; HIT-40; MGC71805; OTTHUMP00000209843; Protein for MGC71805; Zinc finger protein 14; Zinc finger protein 799; Zinc finger protein 842; Zinc finger protein HIT 40; ZN799_HUMAN; ZNF799; ZNF842.
研究领域 : 转录调节因子 锌指蛋白 表观遗传学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human,
产品应用 : WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 71kDa
细胞定位 : 细胞核
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human ZNF799:421-520/643
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
PubMed : PubMed
产品介绍 : HIT-40 is a 643 amino acid nuclear protein that belongs to the Kr黳pel C2H2-type zinc-finger protein family. Containing eighteen C2H2-type zinc fingers and one KRAB domain, HIT-40 may be involved in transcriptional regulation. HIT-40 exists as two isoforms due to alternative splicing events, and is encoded by a gene that maps to human chromosome 19p13.2. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families, and Fc?receptors. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19.
Function:
May be involved in transcriptional regulation.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 18 C2H2-type zinc fingers.
Contains 1 KRAB domain.
SWISS:
Q96GE5
Gene ID:
90576
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片