产品货号 :  mlR19317

英文名称 :  NOM1

中文名称 :  核仁结构域蛋白NOM1抗体

别    名 :  C7orf3; FLJ16401; NOM1; NOM1_HUMAN; Nucleolar MIF4G domain-containing protein 1; SGD1; SGD1 homolog.  

研究领域 :  细胞生物  信号转导  激酶和磷酸酶  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Rabbit,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  96kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human NOM1:31-130/860

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box RNA helicases (see EIF4A1; MIM 602641) (Simmons et al., 2005 [PubMed 15715967]).[supplied by OMIM, Mar 2008]

Function:

Plays a role in targeting PPP1CA to the nucleolus.

Subcellular Location:

Nucleus > nucleolus.

Tissue Specificity:

Expressed in heart and skeletal muscle.

Similarity:

Belongs to the CWC22 family.

Contains 1 MI domain.

Contains 1 MIF4G domain.

SWISS:

Q5C9Z4

Gene ID:

64434

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.