产品货号 :  mlR18096

英文名称 :  HSZFP36/ZNF823

中文名称 :  锌指蛋白823抗体

别    名 :  ZFP 36 for a zinc finger protein; Zinc finger protein 823; Zinc finger protein ZFP 36; ZNF823.  

研究领域 :  细胞生物  转录调节因子  锌指蛋白  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  70kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human HSZFP36/ZNF823:101-200/610

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HSZFP36, also known as ZNF823 (zinc finger protein 823) or ZFP36, is a 610 amino acid member of the Krüppel C2H2-type zinc-finger protein family and is thought be involved in transcriptional regulation. Localized to the nucleus, HSZFP36 contains one KRAB domain and 16 C2H2-type zinc fingers through which it may convey DNA, RNA and protein binding capabilities.

Function:

The cDNA sequence of HSZFP36 was generated by the Mammalian Gene Collection (MGC) Program Team.

Subcellular Location:

Nuclear 

Similarity:

Belongs to the krueppel C2H2-type zinc-finger protein family.

Contains 16 C2H2-type zinc fingers.

Contains 1 KRAB domain.

SWISS:

P16415

Gene ID:

55552

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.