产品货号 : mlR0372
英文名称 : NT5C2
中文名称 : 胞浆-5´-核苷酸酶-Ⅱ抗体
别 名 : 5' nucleotidase (purine) cytosolic type B; 5NTC_HUMAN; cN II; Cytosolic 5''-nucleotidase II; Cytosolic IMP/GMP-specific 5'-nucleotidase; Cytosolic purine 5' nucleotidase; Cytosolic purine 5''-nucleotidase; GMP; NT5B; nt5c2; NT5CP; NUCLEOTIDASE, 5-PRIME, CYTOSOLIC II; NUCLEOTIDASE, 5-PRIME, TYPE B; PNT5; PURINE 5-PRIME-NUCLEOTIDASE; PNT5.
研究领域 : 心血管 细胞生物 免疫学 染色质和核信号 细胞表面分子 表观遗传学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Dog, Cow,
产品应用 : WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 65kDa
细胞定位 : 细胞浆
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human NT5C2:1-100/561
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides. [provided by RefSeq, Oct 2011]
Function:
May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.
Subunit:
Homotetramer.
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the 5'(3')-deoxyribonucleotidase family.
SWISS:
P49902
Gene ID:
22978
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CD-73(胞浆-5´-核苷酸酶-Ⅱ)具有水解酶及磷酸转移酶的活性,在调解核苷酸的平衡中发挥着重要作用.