产品货号 :  mlR16740

英文名称 :  TRIM46

中文名称 :  TRIM46蛋白抗体

别   名 :  fibronectin type-III and C-terminal SPRY motif protein; Gene Y protein; GeneY; TRI46_HUMAN; TRIFIC; Trim46; Tripartite; Tripartite motif containing protein 46; Tripartite motif-containing protein 46; Tripartite, fibronectin type III and C terminal SPRY motif protein.  

研究领域 :  细胞生物  免疫学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rabbit,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  83kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human TRIM46:401-500/759

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background:

TRIM46 is a 759 amino acid intracellular protein that contains a variety of domains that are characteristic to TRIM proteins, including a RING-type zinc finger and a B box-type zinc finger. All subclass members, including TRIM46, TRIM9, TRIM67 and TRIM36, have conserved domain arrangement and associate with microtubule cytoskeleton, which may suggest that subcellular compartmentalization is determined by the unique domain architecture. The gene encoding TRIM46 is located on human chromosome 1, which spans about 260 million base pairs and comprises nearly 8% of the human genome.

Similarity:

Belongs to the TRIM/RBCC family.

Contains 1 B box-type zinc finger.

Contains 1 B30.2/SPRY domain.

Contains 1 COS domain.

Contains 1 fibronectin type-III domain.

Contains 2 RING-type zinc fingers.

SWISS:

Q7Z4K8

Gene ID:

80128

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.