产品货号 :  mlR16713

英文名称 :  TREX2

中文名称 :  TREX2蛋白抗体

别    名 :  3' 5' exonuclease; 3' 5' exonuclease TREX2; 3'-5' exonuclease TREX2; Three prime repair exonuclease 2; TREX 2; TREX2; TREX2_HUMAN.  

研究领域 :  细胞生物  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  31kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human TREX2:61-160/279

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background:

This gene encodes a nuclear protein with 3' to 5' exonuclease activity. The encoded protein participates in double-stranded DNA break repair, and may interact with DNA polymerase delta. [provided by RefSeq, Nov 2012]

Function:

Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair.

Subcellular Location:

Nucleus.

Tissue Specificity:

Detected in heart, breast, prostate, skeletal muscle, testis, uterus, bone marrow, colon, small intestine, stomach and thymus.

Similarity:

Belongs to the exonuclease superfamily. TREX family.

SWISS:

Q9BQ50

Gene ID:

11219

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.