产品货号 : mlR11411
英文名称 : PTGFR
中文名称 : 前列腺素F2a受体抗体PGF2αR
别 名 : Prostaglandin F2 alpha Receptor PF2R_HUMAN; PGF receptor; PGF2 alpha receptor; PGF2-alpha receptor; Prostaglandin F receptor; Prostaglandin F2-alpha receptor; Prostaglandin receptor 2 alpha; Prostanoid FP receptor; PTGFR; FP; MGC120498; MGC46203.
研究领域 : 细胞生物 神经生物学 信号转导 细胞膜受体 G蛋白偶联受体 G蛋白信号 细胞膜蛋白
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Dog, Horse, Rabbit,
产品应用 : WB=1:500-2000 ELISA=1:500-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 40kDa
细胞定位 : 细胞膜
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human PTGFR:1-50/359 <Extracellular>
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function:
Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
SWISS:
P43088
Gene ID:
5737
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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