产品货号 :  mlR12306

英文名称 :  ZFX

中文名称 :  锌指蛋白X染色体蛋白抗体

别   名 :  X-linked zinc finger protein; zfx; ZFX_HUMAN; Zinc finger protein, X-linked; Zinc Finger X Chromosomal Protein; Zinc finger X-chromosomal protein.  

研究领域 :  细胞生物  发育生物学  信号转导  干细胞  锌指蛋白  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Cow, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  90kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human ZFX:401-500/805

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zfy1 (zinc finger protein 1, Y linked), also known Zfy-1 is a 782 amino acid nuclear protein belonging to the Krüppel C2H2-type zinc-finger protein family and the ZFX/ZFY subfamily. Containing thirteen C2H2-type zinc fingers, Zfy1 is expressed in the genital ridge and adult testis and may be a probable transcription activator. The gene encoding Zfy1 maps to mouse chromosome Y.

Function:

Probable transcriptional activator.

Subcellular Location:

Nucleus.

Similarity:

Belongs to the krueppel C2H2-type zinc-finger protein family.

ZFX/ZFY subfamily. Contains 13 C2H2-type zinc fingers. 

SWISS:

P17010

Gene ID:

7543

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片