产品货号 :  mlR12964

英文名称 :  TAF1L

中文名称 :  TATA盒结合蛋白相关因子1样蛋白抗体

别    名 :  MGC134910; TAF 1L; TAF(II)210; TAF1 like RNA polymerase II TATA box binding protein (TBP) associated factor 210kD; TAF1 like RNA polymerase II TATA box binding protein (TBP) associated factor 210kDa; TAF1 RNA polymerase II TATA box binding protein (TBP) associated factor 210kDa like; TAF1L; TAF1L_HUMAN; TAF2A2; TBP associated factor 1 like; TBP associated factor 210 kDa; TBP associated factor RNA polymerase 1 like; TBP-associated factor 1-like; TBP-associated factor 210 kDa; Transcription initiation factor TFIID 210 kDa subunit; Transcription initiation factor TFIID subunit 1 like; Transcription initiation factor TFIID subunit 1-like.  

研究领域 :  转录调节因子  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  207kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human TAF1L:

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  This locus is intronless, and apparently arose in the primate lineage from retrotransposition of the transcript from the multi-exon TAF1 locus on the X chromosome. The gene is expressed in male germ cells, and the product has been shown to function interchangeably with the TAF1 product. [provided by RefSeq, Aug 2009]

Function:

May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced.

Subcellular Location:

Nucleus.

Tissue Specificity:

Testis specific, expressed apparently in germ cells.

Similarity:

Belongs to the TAF1 family.

Contains 2 bromo domains.

SWISS:

Q8IZX4

Gene ID:

138474

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.