产品货号 :  mlR18253

英文名称 :  Tapasin Related Protein

中文名称 :  TAP结合蛋白样抗体

别    名 :  FLJ10143; TAP binding protein like; TAP binding protein related; TAP binding protein related protein; TAP-binding protein-like; TAP-binding protein-related protein; Tapasin like; Tapasin R; Tapasin-like; TAPASIN-R; Tapasin-related protein; TAPBP L; TAPBP R; TAPBP-R; Tapbpl; TAPBPR; TPSNR_HUMAN.  

研究领域 :  细胞生物  免疫学  信号转导  结合蛋白  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Horse,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  49kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human Tapasin Related Protein:301-400/468

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   Tapasin, or TAPBP (MIM 601962), is a member of the variable-constant Ig superfamily that links major histocompatibility complex (MHC) class I molecules to the transporter associated with antigen processing (TAP; see MIM 170260) in the endoplasmic reticulum (ER). The TAPBP gene is located near the MHC complex on chromosome 6p21.3. TAPBPL is a member of the Ig superfamily that is localized on chromosome 12p13.3, a region somewhat paralogous to the MHC.[supplied by OMIM, Mar 2008]

Subcellular Location:

Cell membrane. Endoplasmic reticulum membrane. Microsome membrane. Mainly found in endoplasmic reticulum but a minority is found on the cell surface.

Similarity:

Contains 1 Ig-like C1-type (immunoglobulin-like) domain.

Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:

Q9BX59

Gene ID:

55080

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.