产品货号 :  mlR8693

英文名称 :  PTPLAD1

中文名称 :  蛋白酪氨酸磷酸酶样A结构域蛋白1抗体

别    名 :  B IND1; Butyrate induced protein 1; Butyrate induced transcript 1; FLJ90376; hB ind1; HSPC121; Protein tyrosine phosphatase like A domain containing 1; PTPLAD 1.  

研究领域 :  细胞生物  信号转导  激酶和磷酸酶  表观遗传学  G蛋白信号  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  43kDa

细胞定位 :  细胞浆 细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human PTPLAD1:1-100/362 <Cytoplasmic>

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background:

PTPLAD1 is a component of Rac1-signaling pathways leading to the modulation of gene expression. It potentiates different effects of the small GTPase Rac1, such as c-Jun N-terminal kinase activation and transcriptional activity of nuclear factor kappaB (NF-kappaB).It plays a crucial role in HCV RNA replication and the propagation of JFH1 virus through interaction with viral and host proteins.

Subcellular Location:

Membrane; Multi-pass membrane protein.

Similarity:

Belongs to the very long-chain fatty acids dehydratase HACD family.

Contains 1 CS domain.

SWISS:

Q9P035

Gene ID:

51495

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片