产品货号 : mlR17256
英文名称 : SC5DL
中文名称 : SC5DL蛋白抗体
别 名 : 3beta hydroxysteroid delta5 desaturase; C 5 sterol desaturase; Delta 5 desaturase like; Delta(7) sterol 5 desaturase; ERG3; Fungal ERG3; Lathosterol 5 desaturase; Lathosterol oxidase; MGC93101; S5DES; SC5D; Sterol C5 desaturase (ERG3 delta 5 desaturase homolog, S. cerevisiae) like; Sterol C5 desaturase.
研究领域 : 肿瘤 细胞生物 信号转导 转录调节因子 表观遗传学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Dog, Pig, Horse,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 35kDa
细胞定位 : 细胞浆
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human SC5DL:201-299/299
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : This gene encodes an enzyme of cholesterol biosynthesis. The encoded protein catalyzes the conversion of lathosterol into 7-dehydrocholesterol. Mutations in this gene have been associated with lathosterolosis. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
Function:
SC5DL catalyzes the conversion of lathosterol into 7 dehydrocholesterol. Mutations in this gene have been associated with lathosterolosis.
Subcellular Location:
Endoplasmic reticulum membrane; Multipass membrane protein
SWISS:
O75845
Gene ID:
6309
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.