产品货号 :  mlR20483

英文名称 :  Secretory phospholipase A2

中文名称 :  分泌型磷脂酶A2抗体

别    名 :  C 3.1.1.4; GIIC sPLA2; Group IIA phospholipase A2; membrane associated; Modifier of MIN 1 mouse homolog; MOM1; Non-pancreatic secretory phospholipase A2; NPS PLA2; NPS-PLA2; PA2GA_HUMAN; Phosphatidylcholine 2-acylhydrolase 2A; Phosphatidylcholine 2acylhydrolase; Phospholipase A2; Phospholipase A2 group IIA (platelets, synovial fluid); Phospholipase A2 membrane associated; Phospholipase A2 polypeptide B; Phospholipase A2 synovial; PLA2; PLA2B; PLA2G2A; PLA2L; PLA2S; PLAS1; RASF A; sPLA2.  

研究领域 :  细胞生物  细胞膜蛋白  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Mouse, Rat,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  14kDa

细胞定位 :  细胞膜 分泌型蛋白

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from mouse Secretory phospholipase A2:23-100/146

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background:

The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009].

Function:

Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.

Subcellular Location:

Membrane.

Similarity:

Belongs to the phospholipase A2 family.

SWISS:

P31482

Gene ID:

18780

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片