产品货号 : mlR18857
英文名称 : RRP12
中文名称 : RRP12样蛋白抗体
别 名 : ribosomal RNA processing 12 homolog (S. cerevisiae); Rrp12; RRP12-like protein; RRP12_HUMAN.
研究领域 : 细胞生物 免疫学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep,
产品应用 : IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 144kDa
细胞定位 : 细胞核
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human RRP12:1-100/1297
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : RRP12 is a 1,297 amino acid single-pass membrane protein that participates in ribosomal assembly. Expressed in testis and ovary, RRP12 belongs to the RRP12 family and localizes to the nucleus. RRP12 may be involved in coupling the control of ribosome production to the regulation of other cellular processes during cell cycle progression. In conjunction with Dim2, RRP12 is thought to be involved in the nucleocytoplasmic translocation of pre-ribosomes during ribosome assembly. RRP12 exists two alternatively spliced isoforms and is encoded by a gene located on human chromosome 10q24.1.
Subcellular Location:
Nucleus > nucleolus. Nucleus membrane.
Tissue Specificity:
Weakly expressed. Expressed at intermediate level in testis and ovary.
Similarity:
Belongs to the RRP12 family.
SWISS:
Q5JTH9
Gene ID:
23223
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.