产品货号 :  mlR18579

英文名称 :  LYPLA3

中文名称 :  溶酶体磷脂酶3抗体

别 名 :  1 O acylceramide synthase; 1-O-acylceramide synthase; ACS; DKFZp564A0122; Group XV phospholipase A2; GXVPLA 2; GXVPLA2; LCAT like lysophospholipase; LCAT-like lysophospholipase; LLPL; LPLA 2; LPLA2; LYPLA 3; Lysophospholipase 3 (lysosomal phospholipase A2); Lysophospholipase 3; Lysosomal phospholipase A2; OTTHUMP00000174859; PAG15_HUMAN; Phospholipase A2, group XV; PLA2G15; UNQ341/PRO540.  

研究领域 :  肿瘤  细胞生物  新陈代谢  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Rabbit,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  43kDa

细胞定位 :  分泌型蛋白

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human LYPLA3:101-200/412

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities. [provided by RefSeq, Jul 2008]

Function:

Has transacylase and calcium-independent phospholipase A2 activity. Catalyzes the formation of 1-O-acyl-N-acetylsphingosine and the concomitant release of a lyso-phospholipid (By similarity). May have weak lysophospholipase activity.

Subcellular Location:

Lysosome. Secreted.

Tissue Specificity:

Highly expressed in heart, placenta, skeletal muscle, kidney and pancreas. Detected at lower levels in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes.

Post-translational modifications:

N-glycosylated.

Similarity:

Belongs to the AB hydrolase superfamily. Lipase family.

SWISS:

Q8NCC3

Gene ID:

23659

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片