产品货号 :  mlR7380

英文名称 :  RhoGAP5

中文名称 :  Rho GTP酶激活蛋白5抗体

别    名 :  Arhgap5; Rho GTPase activating protein 5 ARHGAP 5; ARHGAP5; RHG05_HUMAN; p190 B; p190 RhoGAP; Rho GTPase activating protein 5; RhoGAP 5; RhoGAP; RhoGAP5.  

研究领域 :  细胞生物  信号转导  激酶和磷酸酶  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  172kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human RhoGAP5:251-350/1502

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:

GTPase-activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of RASA1/p120GAP.

Subcellular Location:

Cytoplasmic.

Tissue Specificity:

Expressed in kidney, brain, liver and lung.

Similarity:

Contains 4 FF domains.

Contains 1 Rho-GAP domain.

SWISS:

Q13017

Gene ID:

394

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.