产品货号 : mlR18956
英文名称 : MLN64
中文名称 : 淋巴结转移的基因64蛋白抗体
别 名 : CAB 1; CAB1; Es 64; Es64; FLJ41370; Metastatic lymph node gene 64 protein; Metastatic lymph node protein 64; MLN 64; Mln64; Protein CAB 1; Protein CAB1; Protein MLN 64; Protein MLN64; StAR related lipid transfer protein 3; StAR-related lipid transfer protein 3; STAR3_HUMAN; STARD 3; StARD3; START domain containing 3; START domain-containing protein 3; Steroidogenic acute regulatory protein related.
研究领域 : 肿瘤 细胞生物 信号转导 淋巴细胞
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 51kDa
细胞定位 : 细胞浆
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human MLN64:181-280/445
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
Function:
Binds and transports cholesterol. Promotes steroidogenesis in placenta and brain.
Subunit:
Can form homodimers. Interacts with STARD3NL.
Subcellular Location:
Late endosome membrane.
Similarity:
Contains 1 MENTAL domain.
Contains 1 START domain.
SWISS:
Q14849
Gene ID:
10948
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
