产品货号 :  mlR8028

英文名称 :  CNKSR1

中文名称 :  Ras激酶抑制因子连接增强蛋白1抗体

别    名 :  CNK； CNK homolog protein 1； CNK1； CNKR1_HUMAN； CNKSR1； Connector enhancer of kinase suppressor of ras 1； Connector enhancer of KSR 1； Connector enhancer of KSR like； Connector enhancer of KSR-like； Connector enhancer of KSR1； hCNK1； KSR.  

研究领域 :  细胞生物  免疫学  信号转导  G蛋白信号  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  80kDa

细胞定位 :  细胞浆 细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human CNKSR1:621-720/720

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway. [provided by RefSeq, Jul 2008].

Function:

May function as an adapter protein or regulator of Ras signaling pathways.

Subunit:

Interacts with RHO and RALGDS.

Subcellular Location:

Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity).

Post-translational modifications:

Phosphorylated on tyrosine.

Similarity:

Belongs to the CNKSR family.

Contains 1 CRIC domain.

Contains 1 PDZ (DHR) domain.

Contains 1 PH domain.

Contains 1 SAM (sterile alpha motif) domain.

SWISS:

Q969H4

Gene ID:

10256

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片