产品货号 : mlR19733
英文名称 : RASEF
中文名称 : ras基因相关蛋白Rab45抗体
别 名 : FLJ31614; RAB45; RAB45 member RAS oncogene family; RASEF_HUMAN; RAS and EF hand domain containing; RAS and EF hand domain containing protein; Ras related protein Rab 45.
研究领域 : 肿瘤 细胞生物 信号转导 G蛋白偶联受体 G蛋白信号
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 83kDa
细胞定位 : 细胞浆
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human RASEF:551-650/740
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene. [provided by RefSeq, Nov 2012]
Function:
Binds predominantly GDP, and also GTP.
Subcellular Location:
Cytoplasm, perinuclear region.
Tissue Specificity:
Down-regulated in cutaneous melanoma cells but not in breast cancer cells.
Similarity:
Belongs to the small GTPase superfamily. Rab family.
SWISS:
Q8IZ41
Gene ID:
158158
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
