产品货号 :  mlR3868

英文名称 :  Rab24

中文名称 :  ras基因相关蛋白Rab24抗体

别    名 :  OTTHUMP00000161435; OTTHUMP00000161437; OTTHUMP00000223588; Rab 24; RAB24; RAB24, member RAS oncogene family; RAB24_HUMAN; Ras related protein Rab 24; Ras-related protein Rab-24.  

研究领域 :  肿瘤  免疫学  信号转导  新陈代谢  线粒体  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应  :  Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  23kDa

细胞定位 :  细胞浆 细胞膜 线粒体

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human Rab24:1-100/203

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background:

A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.

Function:

May be involved in autophagy-related processes (By similarity).

Subunit:

Unlike other Rab family members, does not interact with GDP dissociation inhibitors (GDIs), including ARHGDIA and ARHGDIB. Interacts with ZFYVE20.

Subcellular Location:

Cytoplasm, cytosol. Membrane; Lipid-anchor.

Post-translational modifications:

Isoprenylation is inefficient compared to other Rab family members.

Similarity:

Belongs to the small GTPase superfamily. Rab family.

SWISS:

Q969Q5

Gene ID:

53917

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片