产品货号 : mlR18881
英文名称 : RSU1
中文名称 : ras癌基因蛋白1抗体
别 名 : FLJ31034; Ras suppressor protein 1; Ras suppressor protein 1 isoform 1; RSP 1; RSP-1; RSP1; RSU 1; Rsu-1; RSU1; RSU1 protein; RSU1_HUMAN.
研究领域 : 细胞生物 信号转导 G蛋白信号
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 31kDa
细胞定位 : 细胞膜
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human RSU1:1-100/277
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors. [provided by RefSeq, Jul 2008]
Function:
Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro.
Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side
Tissue Specificity:
Highly expressed in heart and brain.
Similarity:
Contains 7 LRR (leucine-rich) repeats.
SWISS:
Q15404
Gene ID:
6251
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.