产品货号 :  mlR21058

英文名称 :  PPFIBP2

中文名称 :  PTPRF相互作用蛋白结合蛋白2抗体

别    名 :  Binding protein 2; Cclp 1; Cclp1; DKFZp781K06126; LIPB2_HUMAN; Liprin beta 2; Liprin-beta-2; MGC42541; PPFIBP 2; Ppfibp2; Protein tyrosine phosphatase receptor type f polypeptide interacting protein binding protein 2; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2; PTPRF interacting protein binding protein 2 (liprin beta 2); PTPRF interacting protein binding protein 2; PTPRF-interacting protein-binding protein 2.  

研究领域 :  细胞生物  神经生物学  信号转导  激酶和磷酸酶  结合蛋白  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,

产品应用 :  IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  99kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human PPFIBP2:601-700/876

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  This gene encodes a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. The encoded protein is a beta liprin and plays a role in axon guidance and neuronal synapse development by recruiting LAR protein-tyrosine phosphatases to the plasma membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

Function:

May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.

Tissue Specificity:

Widely expressed.

Similarity:

Belongs to the liprin family.

Liprin-beta subfamily.

Contains 3 SAM (sterile alpha motif) domains.

SWISS:

Q8ND30

Gene ID:

8495

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.