产品货号 :  mlR19184

英文名称 :  PROSC

中文名称 :  PROSC蛋白抗体

别    名 :  FLJ11861; Proline synthase co-transcribed bacterial homolog protein; Proline synthetase co transcribed bacterial homolog; Proline synthetase co transcribed homolog (bacterial); PROSC; PROSC_HUMAN.  

研究领域 :  肿瘤  细胞生物  信号转导  泛素  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  30kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human PROSC:1-100/275

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   PROSC is a 275 amino acid ubiquitously expressed enzyme that is highly conserved from bacteria to mammals. The gene encoding PROSC is cotranscribed with proline sythetase. PROSC requires the cofactor pyridoxal phosphate, the active form of vitamin B6 that acts in all transamination reactions. The PROSC gene maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Tissue Specificity:

Ubiquitous.

Similarity:

Belongs to the UPF0001 family.

SWISS:

O94903

Gene ID:

11212

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.