产品货号 :  mlR9174

英文名称 :  RNF22/TRIM3

中文名称 :  环指蛋白22抗体

别   名 :  TRIM3; BERP; Brain expressed RING finger protein; FLJ16135; HAC1; Ring finger protein 22; RNF22; RNF9; Tripartite motif containing 3  

研究领域 :  细胞生物  免疫学  

抗体来源 :  Rabbit

克隆类型vPolyclonal

交叉反应 :   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  81kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human TRIM3/RNF22:301-400/744

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   BERP; Brain expressed RING finger protein; FLJ16135; HAC1; Ring finger protein 22; RNF22; RNF9; Tripartite motif containing 3.

Function:

Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.

Subunit:

Associates with myosin-Vb (MYO5B) and alpha-actinin-4 (ACTN4) (By similarity). Component of the CART complex, at least composed of ACTN4, HGS/HRS, MYO5B and TRIM3. Interacts with ZFYVE28/LST2.

Subcellular Location:

Cytoplasmic

Tissue Specificity:

Expressed in brain, heart, uterus and testis.

Similarity:

Belongs to the TRIM/RBCC family.

Contains 1 B box-type zinc finger.

Contains 1 filamin repeat.

Contains 6 NHL repeats.

Contains 1 RING-type zinc finger.

SWISS:

O75382

Gene ID:

10612

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片