产品货号 :  mlR17568

英文名称 :  OTUD7A

中文名称 :  OTUD7A蛋白抗体

别    名 :  C15orf16; OTU domain containing protein 7A; OTU domain-containing protein 7A; OTU7A_HUMAN; OTUD7; OTUD7A; Zinc finger protein Cezanne 2.  

研究领域 :  细胞生物  表观遗传学  泛素  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  101kDa

细胞定位 :  细胞核 细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human OTUD7A:501-600/926

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. OTUD7A belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM, May 2008]

Function:

Has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin.

Subcellular Location:

Cytoplasm. Nucleus.

Similarity:

Belongs to the peptidase C64 family.

Contains 1 A20-type zinc finger.

Contains 1 OTU domain.

SWISS:

Q8TE49

Gene ID:

161725

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.