产品货号 :  mlR17534

英文名称 :  OTOP1

中文名称 :  OTOP1蛋白抗体

别    名 :  A530025J20Rik; otop1; OTOP1_HUMAN; Otopetrin-1; Otp1; Tilted; tlt.  

研究领域 :  细胞生物  信号转导  G蛋白信号  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  67kDa

细胞定位 :  细胞膜 分泌型蛋白

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human OTOP1:321-420/612

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  Required for normal formation of otoconia in the inner ear. Inhibits P2Y purinoceptors. Modulates calcium homeostasis and influx of calcium in response to extracellular ATP.

Subcellular Location:

Membrane. Secreted > extracellular space. Detected in the gelatinous membrane overlying the inner ear macular epithelium.

Similarity:

Belongs to the otopetrin family.

SWISS:

Q7RTM1

Gene ID:

133060

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.