产品货号 :  mlR18701

英文名称 :  MBD3L1

中文名称 :  甲基化CpG结合域蛋白3样1抗体

别    名 :  MB3L1_HUMAN; MBD3 like 1; MBD3-like protein 1; MBD3L; Mbd3l1; Methyl CpG binding domain protein 3 like 1; Methyl-CpG-binding domain protein 3-like 1.  

产品类型 :  甲基化抗体

研究领域 :  转录调节因子  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  22kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human MBD3L1:1-100/194

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍  :  This gene encodes a protein that is related to methyl-CpG-binding proteins but lacks the methyl-CpG binding domain. The protein is localized to discrete areas in the nucleus, and expression appears to be restricted to round spermatids, suggesting that the protein plays a role in the postmeiotic stages of male germ cell development. [provided by RefSeq, Jul 2008]

Function:

Transcriptional repressor.

Subcellular Location:

Nucleus. Nuclear, in large foci.

Tissue Specificity:

Highly expressed in testis. Detected at low levels in pancreas. Not detected in the other tissues tested.

Similarity:

Belongs to the MBD3L family.

SWISS:

Q8WWY6

Gene ID:

85509

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.