产品货号 :  mlR19018

英文名称 :  Nardilysin

中文名称 :  N精氨酸二元转化蛋白NRD1抗体

别    名 :  EC 3.4.24.61; hNRD1; hNRD2; N arginine dibasic convertase; Nardilysin precursor; NRD C; NRD convertase; NRD1.  

研究领域 :  细胞生物  泛素  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  132kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human Nardilysin:51-150/1150

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

Function:

Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.

Tissue Specificity:

Primarily in adult heart, skeletal muscle, and testis and at much lower levels in other tissues.

Similarity:

Belongs to the peptidase M16 family.

SWISS:

O43847

Gene ID:

4898

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.