产品货号 :  mlR19511

英文名称 :  NUDT14

中文名称 :  NUDT14蛋白抗体

别    名 :  Nucleoside diphosphate linked moiety X type motif 14; Nucleoside diphosphate-linked moiety X motif 14; NUD14_HUMAN; Nudix (nucleoside diphosphate linked moiety X) type motif 14; Nudix motif 14; NUDT14; UDP sugar diphosphatase; UDPG pyrophosphatase; UGPP; UGPPase; Uridine diphosphate glucose pyrophosphatase.  

研究领域 :  细胞生物  免疫学  信号转导  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Cow, Horse, Sheep, Guinea Pig,

产品应用 :  IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  24kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human NUDT14:1-100/222

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  UDP-glucose (UDPG) acts as the sugar donor in numerous glycosylation reactions, including those involved in the production of glycogen. NUDT14 is a UDPG pyrophosphatase (EC 3.6.1.45) that hydrolyzes UDPG to produce glucose 1-phosphate and UMP (Yagi et al., 2003 [PubMed 12429023]).[supplied by OMIM, Mar 2008]

Function:

Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose.

Subcellular Location:

Cytoplasm.

Similarity:

Belongs to the Nudix hydrolase family.

Contains 1 nudix hydrolase domain.

SWISS:

O95848

Gene ID:

256281

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.