产品货号 : mlR19521
英文名称 : NUDT5
中文名称 : NUDT5蛋白抗体
别 名 : ADP sugar pyrophosphatase; ADP-sugar pyrophosphatase; hYSAH 1; hYSAH1; Nucleoside diphosphate linked moiety X motif 5; Nucleoside diphosphate linked moiety X type motif 5; Nucleoside diphosphate-linked moiety X motif 5; Nudix (nucleoside diphosphate linked moiety X) type motif 5; Nudix motif 5; Nudix type motif 5; NUDT 5; Nudt5; NUDT5_HUMAN; YSA1; YSA1H.
研究领域 : 细胞生物 信号转导 表观遗传学
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human,
产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 24kDa
细胞定位 : 细胞浆
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human NUDT5:1-80/219
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013]
Function:
Hydrolyzes with similar activities ADP-ribose, ADP-mannose, and ADP-glucose. Can also hydrolyze other nucleotide sugars with low activity.
Tissue Specificity:
Widely expressed. Most abundant in liver.
Similarity:
Belongs to the Nudix hydrolase family.
Contains 1 nudix hydrolase domain.
SWISS:
Q9UKK9
Gene ID:
11164
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
