产品货号 :  mlR18854

英文名称 :  METTL8

中文名称 :  甲基化样蛋白8抗体

别    名 :  tension induced inhibited protein; methyltransferase like 8; methyltransferase like protein 8; TIP.  

研究领域 :  细胞生物  免疫学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Dog, Pig, Horse,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  32kDa

细胞定位 :  细胞核 细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human METTL8:1-100/291

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  METTL8 is a 291 amino acid cytoplasmic and nuclear protein that exists as multiple alternatively spliced isoforms and is thought to function as a methyltransferase. METTL8 is a member of the methyltransferase superfamily, which includes DNA methyltransferases (Dnmt), histone methyltransferases, catechol-O-methyl transferases and many others. Members of the methyltransferase superfamily have enzymatic activity that results in the transfer of a methyl group to and from DNA, RNA or amino acids. METTL8 is encoded by a gene located on human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome.

Function:

Probable methyltransferase

Subunit:

Interacts with EP300

Subcellular Location:

Cytoplasmic and Nuclear

Similarity:

Belongs to the methyltransferase superfamily. METL family.

SWISS:

Q9H825

Gene ID:

79828

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.