产品货号 :  mlR19483

英文名称 :  NSUN5P2

中文名称 :  NSUN5P2蛋白抗体

别    名 :  FLJ11626; MGC129801; MGC15057; NOL1/NOP2/Sun domain family member 5C; NOL1R2; NOP2/Sun domain family, member 5 pseudogene 2; NOP2/Sun domain family, member 5C (pseudogene); NOP2/Sun domain family, member 5C; NSUN5C; Putative methyltransferase NSUN5C; WBSCR20B; WBSCR20C; Williams-Beuren syndrome chromosomal region 20C protein.  

研究领域 :  细胞生物  免疫学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  34kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human NSUN5P2:231-315/315

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   This locus represents a transcribed pseudogene of a nearby locus on chromosome 7, which encodes a putative methyltransferase. There is also a third closely related pseudogene locus in this region. There is extensive alternative splicing at this locus. [provided by RefSeq, Jul 2013]

Function:

May have S-adenosyl-L-methionine-dependent methyl-transferase activity.

Tissue Specificity:

Ubiquitous.

DISEASE:

NSUN5C is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.

Similarity:

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

SWISS:

Q63ZY6

Gene ID:

260294

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.