产品货号 :  mlR12776

英文名称 :  VPS41

中文名称 :  液泡蛋白分选蛋白41抗体

别    名 :  HVPS41; hVps41p; HVSP41; S53; Vacuolar assembly protein 41; Vacuolar protein sorting 41 (yeast homolog); Vacuolar protein sorting 41 (yeast); Vacuolar protein sorting 41 homolog (S. cerevisiae); Vacuolar protein sorting associated protein 41 homolog; vacuolar protein sorting-associated protein 41 homolog; VPS 41.  

研究领域 :  细胞生物  信号转导  转运蛋白  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Chicken, Rabbit, Guinea Pig,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  96kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human VPS41:1651-1750/4388

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known. [provided by RefSeq, Jul 2008]

Function:

Required for vacuolar assembly and vacuolar traffic.

Subcellular Location:

Cytoplasmic face of coated pits and vesicles.

Similarity:

Belongs to the VPS41 family.

Contains 1 CHCR (clathrin heavy-chain) repeat.

Contains 1 RING-type zinc finger.

SWISS:

P49754

Gene ID:

27072

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.