产品货号 :  mlR9703

英文名称 :  S100A18

中文名称 :  角化蛋白S100A18抗体

别    名 :  S100 calcium binding protein A18, pseudogene 1; S100a18; 1110033K19Rik; Intermediate filament protein; S100 calcium binding protein A17, pseudogene 1; S100A16; S100a18 ps1; HORN_HUMAN.  

研究领域 :  细胞生物  信号转导  细胞周期蛋白  细胞分化  细胞骨架  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  282kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human Hornerin/S100A18:1-100/2850

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background:

Hornerin has similar structural features to those of profilaggrin, an essential protein for keratinization of epidermal tissues. Hornerin may play a role in cornification.

Function:

May play a role in cornification.

Subcellular Location:

Cytoplasmic granule.

Tissue Specificity:

Expressed in psoriatic and regenerating skin after wounding.

Post-translational modifications:

Processed during the process of epidermal differentiation (By similarity).

Similarity:

Belongs to the S100-fused protein family.

In the N-terminal section; belongs to the S-100 family.

Contains 2 EF-hand domains.

SWISS:

Q86YZ3

Gene ID:

388697

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.