产品货号 :  mlR2080

英文名称 :  Cecropin

中文名称 :  抗菌肽/天蚕素抗体

产品类型 :  植物抗体

研究领域 :  细菌及病毒  植物  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Hyalophora cecropia

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  4kDa

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide from Hyalophora cecropia Cecropin:1-37/41

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   Cecropins are antimicrobial peptides.They were first isolated from the hemolymph of Hyalophora cecropia, from whence the term cecropin was derived. Cecropins lyse bacterial cell membranes; they also inhibit proline uptake and cause leaky membranes. Cecropins constitute a main part of the cell-free immunity of insects. Cecropins are small proteins of about 31 - 37 amino acid residues active against both Gram-positive and Gram-negative bacteria. Cecropins isolated from insects other than Hyalophora cecropia (Cecropia moth) have been given various names; bactericidin, lepidopteran, sarcotoxin, etc. All of these peptides are structurally related. Cecropin P1, an intestinal antibacterial peptide from Sus scrofa (Pig), also belongs to this family. Cecropin family also consists Cecropin A and Cecropin B.

Function:

Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.

Subcellular Location:

Secreted.

Post-translational modifications:

A protein with the same sequence as cecropin A, but lacking the carboxyl blocking group, has been isolated and called cecropin C (PubMed:7140755).

Similarity:

Belongs to the cecropin family.

SWISS:

N/A

Gene ID:

N/A

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Cecropin抗菌肽又称天蚕素，具有抗菌、抗病毒、抗肿瘤等活性，因其水溶性好，耐高温，是一种比较理想的抗生素代用品；尤其是其主要抑菌机制,可破坏细胞膜的稳定性，不易产生耐药性。 抗菌肽一般是小肽，可以被动物完全消化，不存在残留性的问题，所以，抗菌肽无论是作为饲料添加剂，兽药还是人药，都有理论上的研究价值和生产中的实际意义。