产品货号 :  mlR16731

英文名称 :  TRIM29 (acetyl K116)

中文名称 :  乙酰化TRIM29蛋白抗体

别    名 :  Ataxia telangiectasia group D associated protein; Ataxia telangiectasia group D-associated protein; ATDC; FLJ36085; TRI29_HUMAN; TRIM 29; TRIM29; Tripartite motif containing 29; Tripartite motif containing protein 29; Tripartite motif protein 29; Tripartite motif protein TRIM29; Tripartite motif-containing protein 29.  

产品类型 :  乙酰化抗体

研究领域 :  细胞生物  免疫学  信号转导  转录调节因子  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Pig, Cow, Rabbit,

产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子量 :  66kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated Synthesised acetylpeptide derived from human TRIM29 around the acetylation site of K116:AK(Ac-K)PP

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background:

The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]

Function:

It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.

Subcellular Location:

Cytoplasm. Colocalizes with intermediate filaments.

Tissue Specificity:

Expressed in placenta, prostate and thymus.

Post-translational modifications:

Constitutively phosphorylated by PKC on serine/threonine in A431 cells.

Similarity:

Contains 1 B box-type zinc finger.

SWISS:

Q14134

Gene ID:

23650

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.