产品货号 :  mlR17705

英文名称 :  MOGAT2

中文名称 :  MOGAT2蛋白抗体

别    名 :  2 acylglycerol O acyltransferase 2; 2-acylglycerol O-acyltransferase 2; Acyl CoA:monoacylglycerol acyltransferase 2; Acyl-CoA:monoacylglycerol acyltransferase 2; DC5; DGAT2L5; Diacylglycerol acyltransferase 2 like protein 5; Diacylglycerol acyltransferase 2-like protein 5; Diacylglycerol O acyltransferase candidate 5; Diacylglycerol O-acyltransferase candidate 5; EC 2.3.1.22; FLJ22644; hDC5; hMGAT2; Mgat1l; MGAT2; MGC119183; MGC119184; MGC119185; MGC189143; mogat2; MOGT2_HUMAN; Monoacylglycerol O acyltransferase 1 like; Monoacylglycerol O acyltransferase 2; Monoacylglycerol O-acyltransferase 2.  

研究领域 :  肿瘤  细胞生物  信号转导  新陈代谢  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  38kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human MOGAT2:51-150/334

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  Dietary fat absorption from the small intestine is facilitated by acyl-CoA:monoacylglycerol transferase (MOGAT; EC 2.3.1.22) and acyl-CoA:diacylglycerol acyltransferase (DGAT; see MIM 604900) activities. MOGAT catalyzes the joining of monoacylglycerol and fatty acyl-CoAs to form diacylglycerol (Yen and Farese, 2003 [PubMed 12621063]).[supplied by OMIM, Mar 2008]

Function:

Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity.

Subcellular Location:

Endoplasmic reticulum membrane.

Tissue Specificity:

Highly expressed in liver, small intestine, colon, stomach and kidney.

Similarity:

Belongs to the diacylglycerol acyltransferase family.

SWISS:

Q3SYC2

Gene ID:

80168

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.