产品货号 :  mlR18737

英文名称 :  MCTP1

中文名称 :  MCTP1蛋白抗体

别    名 :  2810465F10Rik; FLJ22344; MCTP 1; Multiple C2 and transmembrane domain containing protein 1; Multiple C2 domains transmembrane 1; Multiple C2 domains with two transmembrane regions 1; OTTMUSP00000031345; RGD1305199.  

研究领域 :  肿瘤  细胞生物  信号转导  结合蛋白  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  115kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human MCTP1:901-999/999

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   MCTP1 is a 999 amino acid multi-pass membrane protein that belongs to the MCTP family. Existing as five alternatively spliced isoforms, MCTP1 binds calcium via its C2 domains in the absence of phospholipids. The gene encoding MCTP1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Function:

MCTP1 binds calcium via the C2 domains in the absence of phospholipids. There are 5 named isoforms.

Subcellular Location:

Membrane; Multi-pass membrane protein.

SWISS:

Q6DN14

Gene ID:

79772

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.