产品货号 :  mlR18645

英文名称 :  MAN1C1

中文名称 :  MAN1C1蛋白抗体

别    名 :  1 2 alpha mannosidase IC; Alpha 1 2 mannosidase IC; HMIC; MAN1A3; MAN1C; Mannosidase alpha class 1C member 1; Mannosyl oligosaccharide 1 2 alpha mannosidase IC; pp6318; Processing alpha 1 2 mannosidase IC.  

研究领域 :  肿瘤  细胞生物  信号转导  新陈代谢  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Pig,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  71kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human MAN1C1:151-250/630

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   MAN1C1 belongs to the glycosyl hydrolase 47 family. It is involved in the maturation of Asn-linked oligosaccharides. It trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc. MAN1C1 is expressed in most tissues with the exception of lung, muscle and pancreas. It is highly expressed in placenta.

Function:

Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce first Man8GlcNAc2 then Man6GlcNAc and a small amount of Man5GlcNAc.

Tissue Specificity:

Expressed in most tissues with the exception of lung, muscle and pancreas. Highly expressed in placenta.

Similarity:

Golgi apparatus membrane; Single-pass type II membrane protein.

SWISS:

Q9NR34

Gene ID:

57134

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.