产品货号 :  mlR18641

英文名称 :  MAMDC2

中文名称 :  MAMDC2蛋白抗体

别    名 :  MAM domain-containing protein 2; MAM domain-containing proteoglycan; MAMC2_HUMAN; Mamcan; Mamdc2.  

研究领域 :  细胞生物  发育生物学  信号转导  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  75kDa

细胞定位 :  细胞外基质 分泌型蛋白

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human MAMDC2:601-686/686

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  MAMDC2 is a 686 amino acid secreted protein that localizes to extracellular matrix. Containing four MAM domains and existing as two alternatively spliced isoforms, MAMDC2 is encoded by a gene located on human chromosome 9q21.11. Chromosome 9 consists of about 145 million bases, 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, Familial dysautonomia and certain leukemias are also associated with chromosome 9.

Subcellular Location:

Secreted > extracellular space > extracellular matrix.

Post-translational modifications:

O-glycosylated.

Similarity:

Contains 4 MAM domains.

SWISS:

Q7Z304

Gene ID:

256691

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.