产品货号 :  mlR17633

英文名称 :  SPATA6

中文名称 :  精子发生相关蛋白6抗体

别    名 :  1700062C23Rik; AI790763; FLJ10007; Hash; KRP; Mash; RP23 402I22.1; spermatogenesis associated 6; SRF 1; SRF1.  

研究领域 :  细胞生物  发育生物学  干细胞  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  54kDa

细胞定位 :  分泌型蛋白

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human SPATA6:151-250/488

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :  SPATA6 is a 488 amino acid secreted protein that may be involved in spermatid maturation or sperm function. SPATA6 is expressed during embryonic development and is localized in neural tube, somites and limb buds of mouse embryo. Existing as two isoforms produced by alternative splicing events, the gene encoding SPATA6 maps to mouse chromosome 4 and human chromosome 1. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Function:

SPATA6 belongs to the SPATA6 family. SPATA6 may play a role in spermatid maturation or sperm function.

Subcellular Location:

Secreted

Similarity:

Belongs to the SPATA6 family.

SWISS:

Q9NWH7

Gene ID:

54558

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.