产品货号 :  mlR18438

英文名称 :  LSMD1

中文名称 :  LSMD1蛋白抗体

别 名 :  LSM domain-containing protein 1; lsmd1; LSMD1_HUMAN; MAK31; Phosphonoformate immuno-associated protein 2.  

研究领域 :  细胞生物  免疫学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  14kDa

细胞定位 :  细胞核 细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human LSMD1:31-125/125

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   LSmD1 is a 125 amino acid protein that is a component of the N-terminal acetyltransferase C (NatC) complex. Composed of MAK10, NAT-12 and LSmD1, the NatC complex catalyzes the acetylation of amino-terminal methionine residues. siRNA knockdown of NatC complex subunits leads to p53-dependent cell death and reduced growth of cell lines. There are two isoforms of LSmD1 that are produced as a result of alternative splicing events.

Function:

Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues.

Subcellular Location:

Cytoplasm. Nucleus.

Similarity:

Belongs to the snRNP Sm proteins family.

SWISS:

Q9BRA0

Gene ID:

84316

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片