产品货号 :  mlR18433

英文名称 :  LSM8

中文名称 :  LSM8蛋白抗体

别    名 :  2010003I05Rik; AW214405; LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae); MGC127377; YJR022W.  

研究领域 :  细胞生物  结合蛋白  表观遗传学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig,

产品应用 :  IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  10kDa

细胞定位 :  细胞核

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human LSM8:31-96/96

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   This gene encodes a member of the like-Sm family of proteins. The encoded protein consists of a closed barrel shape, made up of five anti-parallel beta strands and an alpha helix. This protein partners with six paralogs to form a heteroheptameric ring which transiently binds U6 small nuclear RNAs and is involved in the general maturation of RNA in the nucleus.

Function:

Binds specifically to the 3'-terminal U-tract of U6 snRNA and is probably a component of the spliceosome.

Subunit:

LSm subunits form a heteromer with a doughnut shape.

Subcellular Location:

Nuclear

Similarity:

Belongs to the snRNP Sm proteins family.

SWISS:

O95777

Gene ID:

51691

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.