产品货号 :  mlR18191

英文名称 :  LCMT2

中文名称 :  LCMT2蛋白抗体

别    名 :  KIAA0547; LCMT 2; Lcmt2; LCMT2_HUMAN; Leucine carboxyl methyltransferase 2; MGC9534; p21WAF1/CIP1 promoter interacting protein; p21WAF1/CIP1 promoter-interacting protein; PPM2; tRNA Wybutosine synthesizing protein 4; tRNA wybutosine synthesizing protein 4 homolog; tRNA wybutosine-synthesizing protein 4 homolog; tRNA yW synthesizing protein 4; tRNA yW synthesizing protein 4 homolog; tRNA yW-synthesizing protein 4 homolog; TYW4.  

研究领域 :  肿瘤  细胞生物  免疫学  信号转导  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :   Human, Mouse, Rat, Cow,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  76kDa

细胞定位 :  细胞浆

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human LCMT2:321-420/686

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍 :   The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW). [provided by RefSeq, Jul 2008]

Function:

Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues.

Similarity:

Belongs to the methyltransferase superfamily. LCMT family.

SWISS:

O60294

Gene ID:

9836

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.