产品货号 :  mlR16800

英文名称 :  KNCN

中文名称 :  KNCN蛋白抗体

别    名 :  FLJ32011; Kino; Kinocilin; Kncn; KNCN_HUMAN; L5; RP11-49P4.2.  

研究领域 :  肿瘤  细胞生物  神经生物学  

抗体来源 :  Rabbit

克隆类型 :  Polyclonal

交叉反应 :  Human,

产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  13kDa

细胞定位 :  细胞膜

性    状 :  Lyophilized or Liquid

浓    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human KNCN:1-100/124

亚    型 :  IgG

纯化方法 :  affinity purified by Protein A

储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

产品介绍background:

Kinocilin is a 124 amino acid multi-pass membrane protein that may play a role in the stabilization of dense microtubular networks, and may also participate in vesicular trafficking. Existing as two alternatively spliced isoforms, the gene encoding Kinocilin maps to human chromosome 1p33 and mouse chromosome 4 D1. Chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. A large number of disease-associated genes are present on chromosome 1, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Function:

May plays a role in stabilizing dense microtubular networks or in vesicular trafficking.

Subcellular Location:

Membrane.

SWISS:

A6PVL3

Gene ID:

148930

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.